Search
Close this search box.

AppliedVR and Kernel Flow Announce Clinical Results Evaluating how Brain Changes During Virtual Reality Treatment of Chronic Pain

men's white dress shirt

LOS ANGELESFeb. 8, 2024 /PRNewswire/ — AppliedVR®, a medical device pioneer advancing a novel, virtual reality-based approach to medicine, and Kernel today announced a joint study measuring the impact of VR pain treatment on the brain. The study, which included a single-blind, sham-controlled design, compared brain activation patterns and physiological metrics before, during, and after VR experiences in people experiencing chronic low back pain (CLBP).

The research used AppliedVR’s RelieVRx® medical device, an eight-week, skills-based program that helps chronic low back pain (CLBP) patients learn self-management skills, combined with Kernel Flow and FlowVR—a compact, affordable, TD-fNIRS brain measurement headset customized for use in VR—to measure brain hemodynamic changes associated with pain relief.

While participants in the RelieVRx and sham groups both experienced varying levels of pain relief after completing the eight-week treatment, researchers determined that participants in the RelieVRx group experienced enhanced brain activation coherence — change that previously has been related to reduced pain — from pre-to-post treatment. Those patients receiving the VR sham control demonstrated a decline in brain coherence.

Additionally, those receiving treatment from the RelieVRx device achieved a slower breathing rate as compared to the sham VR group. These results suggest that active RelieVRx treatment can create physiological changes in the body and have an impact on coherent global brain activity.

Pain is subjective and hard to measure outside of patient-reported outcomes, but affordable and accessible brain imaging could help researchers and providers better understand a patient’s level of pain and the impact of an intervention. AppliedVR and Kernel plan to conduct clinical studies to uncover how RelieVRx as an intervention could drive certain physiological changes in breathing and brain patterns that have been linked to pain relief.

“We’re committed to developing a significant body of scientific evidence that demonstrates how our RelieVRx program, which is rooted in self-regulation, cognitive behavioral therapy skills and mindfulness, engages the brain and can impact the experience of pain,” said AppliedVR Co-founder and President Josh Sackman. “While we know there can be a strong placebo effect, this feasibility study showed that only the active RelieVRx treatment created changes at a physiological and brain activity level, creating a strong foundation for future research.”

Chronic pain costs the U.S. an estimated $635 billion each year and is a major contributing factor driving America’s opioid crisis. Research has suggested that more than 72 million Americans suffer from chronic low back pain, with the condition being a leading cause of disability.

“This exciting research shows how our Kernel Flow technology can measure the brain and help quantify notoriously difficult to measure conditions,” said Kernel CEO Ryan Field. “By unlocking insights into specific biomarkers related to chronic pain, we can continue to help the medical community better understand how treatments like RelieVRx can change the practice of pain medicine.”

This study is part of an ongoing collaboration between AppliedVR and Kernel. Both organizations will continue to deepen and expand their research to larger and more diverse populations.

The Future of Materials Discovery: Reducing R&D Costs significantly with GenMat’s AI and Machine Learning Tools

When: July 13, 2023 at 11:30am

What: GenMat Webinar

Jake Vikoren

Jake Vikoren

Company Speaker

Deep Prasad

Deep Prasad

Company Speaker

Araceli Venegas

Araceli Venegas

Company Speaker

Jack Boreham

Jack Boreham is the editorial director and account executive at the Metaverse Insider: the leading metaverse publication globally. Jack has been at the forefront of the platform's growth as a metaverse specialist -writing and advising projects in the Metaverse space for over two years. [email protected]

Share this article:

Relevant

The Future of Materials Discovery: Reducing R&D Costs significantly with GenMat’s AI and Machine Learning Tools

When: July 13, 2023 at 11:30am

What: GenMat Webinar

Jake Vikoren

Jake Vikoren

Company Speaker

Deep Prasad

Deep Prasad

Company Speaker

Araceli Venegas

Araceli Venegas

Company Speaker

Keep track of everything going on in the Metaverse Technology Market.

In one place.

Related Articles

Join Our Newsletter